Study of Oxidative Stress Marker Serum Paraoxonase in Metabolic Syndrome
نویسندگان
چکیده
منابع مشابه
Serum Paraoxonase/Arylesterase Activity and Oxidative Stress Status in Children with Metabolic Syndrome
OBJECTIVE This study aimed to measure paraoxonase/arylesterase activities and to evaluate the total oxidant and antioxidant capacities in obese children and in children with metabolic syndrome (MetS). METHODS A total of 151 children of comparable ages (13.23±1.96 years, 13.45±1.85 years and 13.95±1.31 years) were enrolled in the study. Forty of these were children with MetS, 55 were obese and...
متن کاملRole of oxidative stress in pathogenesis of metabolic syndrome
The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and cardiovascular diseases, has become one of the major public health challenges worldwide. The pathogenesis of the metabolic syndrome is multiple and still poorly understood. No single factor has yet been identified as an underlying causal factor. There is a growing belief, however, that obesity, specially visceral obe...
متن کاملParaoxonase Activities in Metabolic Syndrome in Children and Adolescents
Background: Metabolic syndrome (MetS) is a collection of various interrelated risk factors that appear to have an impact as development of atherosclerotic cardiovascular disease (CVDs). Epidemic of childhood and adolescent’s obesity has increased interest in the metabolic syndrome (MS) due to the potential projection into adulthood. The prevalence of MS in adolescents has been estimated t...
متن کاملSerum paraoxonase enzyme activity and oxidative stress in obese subjects.
INTRODUCTION Obesity is an important risk factor for atherosclerotic cardiovascular disease. Paraoxonase-1 (PON1) may play a significant role in the prevention of obesity-related accelerated atherosclerosis by hydrolyzing lipid peroxides in oxidized low-density lipoproteins. OBJECTIVES The aim of this study was to evaluate PON1 and arylesterase enzyme activities and lipid hydroperoxide (LOOH)...
متن کاملSerum paraoxonase 1 activity in women with metabolic syndrome.
BACKGROUND Metabolic syndrome (MetS) is a leading risk factor for coronary artery disease (CAD) in women. Reduced paraoxonase 1 (PON1) activity may play a role in the pathogenesis of atherosclerosis through increased susceptibility to lipid peroxidation in patients with MetS. AIM To examine whether there is a relationship between serum PON1 activity and MetS in women. METHOD The study group...
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ژورنال
عنوان ژورنال: Turkish Journal of Endocrinology and Metabolism
سال: 2016
ISSN: 1301-2193
DOI: 10.4274/tjem.3586